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Derivation of TK- clones from revertant TK+ mammalian cells.

In order to obtain a large collection of Chinese hamster cell clones defective in thymidine kinase (TK(-)), BrdU(r) selection experiments have been performed on wild-type and revertant TK(+) cell lines. No clones (< 10(-9)) were obtained from the wild-type TK(+) cell line by single-step selection. In contrast, revertant TK(+) clones readily gave rise to stable TK(-) derivatives (1 - 2 x 10(-4))...

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A Tk OpenGL Widget

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Copyright © 1993 Addison-Wesley Publishing Company, Inc. All rights reserved. Duplication of this draft is permitted by individuals for personal use only. Any other form of duplication or reproduction requires prior written permission of the author or publisher. This statement must be easily visible on the first page of any reproduced copies. The publisher does not offer warranties in regard to...

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ژورنال

عنوان ژورنال: Journal of Orthopaedic & Sports Physical Therapy

سال: 1986

ISSN: 0190-6011,1938-1344

DOI: 10.2519/jospt.1986.7.6.297